![]() From these properties, 10,000 simulated patients were evaluated to determine the pharmacodynamic probability of target attainment for ceftaroline in adults with cystic fibrosis. ![]() From these 16 blood levels, patient-specific pharmacokinetic properties were estimated. In a recent study, 8 patients with cystic fibrosis being treated with ceftaroline each had two blood levels of ceftaroline drawn. Monte Carlo Simulations are commonly employed in pharmacokinetic studies of critically ill patients. The term Monte Carlo is taken from a casino in Monaco and was used as a code word for the technique as it was used during the Manhattan Project.Įxamples of Monte Carlo Simulations in pharmacy literature ![]() Subscribe on iTunes, Android, or StitcherĪ Monte Carlo Simulation in the context of healthcare uses software to simulate thousands of patients from smaller sample sizes to provide a more robust prediction of an event. ![]()
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